Clinical Trials

Julie S. Burt
Supervisor, Ophthalmology Clinical Trials and Regulatory Affairs
New England Eye Center
Tufts Medical Center
800 Washington Street, #450
Boston, MA 02111
617-636-0747 Fax: 617-636-4866
Email: jburt@tuftsmedicalcenter.org

Therapeutic Area

Retina/Ophthalmology

Principal Investigator

Elias Reichel, MD

Title

Phase II, Multicenter, Double-Masked, Placebo Controlled, Parallel Group Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of GSK933776 in Adult Patients with Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

Brief Summary

To test the safety of GSK933776 and to look at any changes in geographic atrophy of the eye over time.

Inclusion Criteria

Evidence of AMD confirmed by the presence of at least 1 druse >125 um diameter in either eye

Exclusion Criteria

Additional eye disease in the study eye that could compromise assessment of BCVA, confound BCVA assessment, or imaging of the posterior pole

Study Requirements

18 study visits over a two year period, additional MRI visits, blood draws, IV infusion

Age Range

55 and over

Gender

Both

Payment

A stipend will be provided for each completed study visit. Transportation to and from your study visits will also be provided to you in addition to the study visit stipend.

Contact

Olivia Sahnas
617-636-1051

Therapeutic Area

Glaucoma/Ophthalmology

Principal Investigator

Cynthia Mattox, MD

Title

A Prospective, Randomized, Comparative, Multicenter Clinical Study To Assess The Safety And Effectiveness Of The Transcend Cypass Glaucoma Implant In Patients With Open Angle Glaucoma Undergoing Cataract Surgery

Brief Summary

The purpose of this research study is to evaluate the safety and effectiveness of the CyPass Implant in lowering intraocular pressure (IOP) in glaucomatous eyes in conjunction with cataract surgery, as compared to eyes treated with cataract surgery alone.

Inclusion Criteria

A diagnosis of primary open angle glaucoma (POAG).

Study Requirements

13 visits

Age Range

45 and over

Gender

Both

Payment

$50 per completed visit

Contact

Melody Velasquez
617-636-5489

Therapeutic Area

Retina/Ophthalmology

Principal Investigator

Elias Reichel, MD

Title

Age Related Macular Degeneration
Biomarkers for Dry Age-Related Macular Degeneration

Brief Summary

This study involves two new tests that could detect whether people have a common eye disease called dry age-related macular degeneration, or dry AMD. These tests may also be useful for monitoring people who already have dry AMD, and deciding whether medication is helping them.

Sponsor: Novartis

Inclusion Criteria

Diagnosed with age-related macular degeneration

Age Range

55 years and older

Gender

Both

Contact

Olivia Sahnas
Clinical Research Coordinator, at
617-636-1051