Specialties
Director of Research
Department of Ophthalmology
Director
Tufts Center for Vision Research
Tufts Medical Center
Education
- PhD, Biochemistry, University of Valladolid (Spain)
Postdoctoral Training
- Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital (Norway)
- Cell Biology and Ophthalmology, Schepens Eye Research Institute, Harvard Medical School (USA)
Biography
Dr. Argüeso grew up in the Basque Country, Spain and received a PhD in Biochemistry from the University of Valladolid in 1997. He conducted postdoctoral research in the Norwegian Radium Hospital and the Schepens Eye Research Institute at Harvard Medical School, where he was appointed Instructor in 2003, Assistant Professor in 2008 and Associate Professor in 2014. In 2022, Dr. Argüeso joined Tufts Medical Center as Director of Research in the Department of Ophthalmology and Director of the Tufts Center for Vision Research.
Dr. Argüeso specializes in corneal diseases and has achieved international recognition for his work studying ocular surface biology. His research focuses on the structure and function of the glycocalyx—a carbohydrate-rich layer lining the surface of eukaryotic cells. His laboratory has developed innovative methods clearly demonstrating the importance of mucins in forming a protective biofilm on epithelial and endothelial cell surfaces. His studies have also uncovered important roles for galectins in the maintenance of ocular surface integrity and immune cell homeostasis, yielding crucial insight into defense mechanisms averting environmental insult and infection. More recent research from his laboratory seeks to define the role of the glycome on pathological remodeling processes associated with wound repair and limbal stem cell deficiency. He has extensively published in high tier peer reviewed journals including Journal of Biological Chemistry, Nature Communications and Science Signaling and has a strong, consistent record of NIH funding of his research.